Column chromatography silica gel properties and uses

The chemical dictionary tells you the characteristics and uses of column chromatography silica gel. Column chromatography silica gel products are made of silica gel, with high transparency and excellent adsorption performance. They have ideal separation functions for similar properties, structures and even isomers.

The properties and uses of column chromatography silica gel.

The properties of column chromatography silica gel

Column chromatography silica gel is white uniform particles, the main component of which is silicon dioxide. It has the characteristics of high purity and hygiene.

It is a colloidal system with solid characteristics, composed of colloidal particles to form an agglomerated structure. Colloidal particles are condensation products of hydrated silica gel (polysilicic acid) and are amorphous substances. The gaps between the colloidal particle aggregates form a microporous structure inside the silica gel particles, which is used for reagent column chromatography. Therefore, it is an adsorption material with rich microporous structure, high specific surface area, high purity and high activity.

The main performance characteristics of reagent column chromatography silica gel-adsorption characteristics, depend on the microporous structure and inner pore surface formed during the production process of raw silica gel.

Uses of column chromatography silica gel

Column chromatography silica gel is used for separation and purification of effective ingredients of traditional Chinese medicine, preparation of high-purity substances, dehydration and purification of petroleum products and organic matter, and outstanding advantages of column chromatography silica gel in the application of bioengineering technology.

In the process of raw material production, the acid bubble and aging time are strictly controlled, and high-temperature calcination technology is adopted. Therefore, the skeleton structure of column chromatography silica gel has good rigidity and high mechanical strength, and can withstand temperature and pressure within 30MPa. Column chromatography silica gel has good thermal stability and chemical stability. It can selectively adsorb and purify isomer components from multi-component solutions. In the process of preparing silica gel for column chromatography, by controlling different process conditions, a series of products with an average pore size of 20A°-20000A° can be produced to adapt to the separation and purification of substances with different properties, molecular weights and molecular structures. The purity of column chromatography silica gel is as high as 99%. Compared with organic column fillers, silica gel is a solid colloid with SiO2 as the matrix and a dense structure. Even if it is directly discarded, the target product will be contaminated by the loss of organic matter.